- P. 294-300.
144. Das B., Sablan E.L., Kilbourne E.J., Fricker L.D. Regulation of carboxypeptidase E by membrane depolarization in PC12 pheochromocythoma cells: comparison with the mRNAs encording other peptide and catecholamines biosynthetic enzymes // Neurochem. - 1992. - 59, N 6. - P. 2263-2270.
145. Davidson H.W., Hutton J.C. The insulin-secretory-granule carboxypeptidase H: Purification and demonstration of involvement in proinsulin processing // Biochem. J. - 1987. - 245, N 2. - P. 575-582.
146. Davis T. P., Gulling-Berglund A. S., Gillespie T. S., Smith T. L. Ethanol treatment alters Я-endorphin metabolism by purified synaptosomal plasma membranes. // Peptides. - 1987. - 8, N 3. - P. 467-472.
147. Demmer W., Brand K. Carboxypeptidase activity in synaptic vesicles isolated from striatum and cortex of calf brain // Arch. Biochem. Biophys. - 1985. - 239, N 2. - P. 375-378.
148. Devaud L.L., Chadda R., Sex-differences in rats in the development of and recovery from ethanol dependence assessed by changes in seizure susceptibility // Alcohol. Clin. Exp. Res. - 2001. - 25, N 11. - P. 1689-1696.
149. Devaud L.L., Fritschy J.M., Morrow A.L. Influence of gender on chronic ethanol induced alterations in GABA(A) receptors in rats // Brain Res. - 1998. - 796, N 1-2. - P. 222-230.
150. Dhanvantari S., Loh Y. P. Lipid raft association of carboxypeptidase E is necessary for its function as a regulated secretory pathway sorting receptor. // J. Biol. Chem. -2000. - 275, N 38. P. 29887-29893.
151. Dochetry K., Hutton J.C. Carboxypeptidase activity in the insulin secretory granule // FEBS Lett. - 1983. - 162, N 1. - P. 137-141.
152. Dronou A., Lucas D., Powell L.W. // Clin. Chem. - 1985. - 31, N 9. - P. 1543-1546.
153. Druse M.J., Hao H.L., Eriksen J.L. In utero ethanol exposure increases proenkephalin, a precursor of a neuropeptide that Is inhibitory to neuronal growth // Alcohol. Clin. Exp. Res. - 1999. - 23, N 9. - P. 1519-1527.
154. Du X.P., Hamre K.M. Increased cell death in the developing vestibulocochlear - ganglion complex of the mouse after prenatal ethanol exposure // Teratology - 2001. - 64, N 6. - P. 301-310.
155. Dufouil C., Ducimetiere P., Alperovitch A., Sex-differences in the association between alcohol consumption and cognitive performance // Amer. J Epidemol. - 1997. - 146, N 5. - P. 405-412.
156. Dulka J.G., Maler L., Ellis W. Androgen-induced changes in electrocommunicatory behavior are correlated with changes in substance P-like immunoreactivity in the brain of the electric fish Apteronotus leptorhynchus // J. Neurosci. - 1995. - 15, № 3 (Pt.1). - P. 1879-1890.
157. Eipper B.A, Green C.B, Mains R.E. Expression of prohormone processing enzymes in neuroendocrine and non neuro-endocrine cells // Monogr. Natl. Cancer. Inst. - 1992. - 13, P. 163-168.
158. Ekstrom J., Ekman R., Hakanson R., Luts A., Sundler F. Developmental studies on vasoactive intestinal peptide, substance P and caleifonin generelated peptide in salivary glands of postnatal rats // Acta Physiol. Scand. - 1994. - 151, № 1. - P. 107-115.
159. Emson P.C., Gilbert R.F.T., Lorer I., Fakrenkrung J., Sundler F., Schaffalitzky de Muckadell O.B. Development of vasoactive intestinal polypeptide (VIP) containing neurons in the rat brain // Brain Res. - 1979. - 177. - P. 437-444.
160. Feng Y., Reznik S. E., Fricker L. D. Distribution of proSAAS derived peptides in rat neuroendocrine tissues. // Neurosci. - 2001. - 105, N 2. P. 469-478.
161. Fiedorek F.T Jr, Parkinson D. Carboxypeptidase H processing and secretion in rat clonal beta cell lines // Endocrinology. - 1992. - 131, N 3. - P. 1054-1062
162. Foster G.A., Schultzbeng M. Immunohistochemical analysis of the ontogeny of neuropeptide Y immunoreactive neurons in foctal rat brain // Int. J.Dev.Neurosci. - 1994. - 2. - P. 387-407.
163. Fricker L.D. Carboxypeptidase E // Ann. Rev. Physiol. - 1988. - 50. - P. 309-321.
164. Fricker L.D. Neuropeptide biosynthesis: focus on carboxypeptidase processing enzyme // Trends Neurosci. - 1985. - 8, № 5. Р. 210-214.
165. Fricker L.D., Adelman J.P., Douglass J., Thompson R.C, von Strandmann R.P, Hutton J AD. Isolation and sequence analysis of cDNA for rat carboxypeptidase E [EC 3.4.17.10], a neuropeptide processing enzyme // Mol. Endocrinol. - 1989. - 3, N 4. - P. 666-673.
166. Fricker L.D., Das B., Angeletti R.H. Identification of the pH dependent membrane anchor of carboxypeptidase E (EC 3.4.17.10) // J. Biol. Chem. - 1990. - 265, N 5. - P. 2476-2282.
167. Fricker L.D., Devi L. Posttranslational processing of carboxypeptidase E, a neuropeptide processing enzyme, in AtT 20 cells and bovine pituitary secretory granules // J. Neurochem. - 1993. - 61, N 4. - P. 1404-1415.
168. Fricker L.D., Herbert E. Comparison of a carboxypeptidase E-like enzyme in human, bovine, mouse, Xenopus, shark and Aplysia neural tissue // Brain Res. - 1988. - 453, N 1-2. - P. 281-286.
169. Fricker L.D., Plummer T.H., Snyder S.H. Enkephalin convertase: potent, selective and irreversible inhibitors // Biochem. and Biophys. Res. Commun. - 1983. - 11, N 3. - P. 994-1000.
170. Fricker L.D., Reaves B.J., Das B., Dannies P.S. Comparison of the regulation of carboxypeptidase E and prolactin in GH4C1 cells, a rat pituitary cell line. // Neuroendocrinology. - 1990. - 51, N 6. - P. 658-663.
171. Fricker L.D., Rigual R. J., Diliberto E. J. Jr., Viveros O. H. Reflex spanchnic nerve stimulation increases levels of carboxypeptidase-E mRNA and enzymatic activity in the rat adrenal medulla // J. Neurochem. - 1990. - 55, N 2. - P. 461-467.
172. Fricker L.D., Snyder S.H. Enkephalin convertase: purification and charasterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenall chromaffin granules // Proc. Natl. Acad. Sci. USA. - 1982. - 79. - P. 3886-3890.
173. Fricker L.D., Snyder S.H. Purification and characterization of enkephalin convertase, an enkephaline-synthesizing carboxypeptidase // J. Biol. Chem. - 1983. - 79. P. 33886-3890.
174. Fricker L.D., Supattapone S., Snyder S.H. Enkephalin convertase: a specific enkephalin synthesing carboxypeptidase in adrenal chromaffin granules, brain and pituitary gland // Life Sci. - 1982. - 31. - P. 1841-1844.
175. Friishansen L., Lacourse K. A., Samuelson L. C., Holst J. J. Attenuated processing of proglucagon and glucagon-like peptide-1 in carboxypeptidase E deficient mice. // J. Endocrinol. - 2001. - 169, N 3. P. 595-602.
176. Friksen S.P., Kulkarni A.B. Methanol in normal human breath // Science - 1963. - 141. - P. 639-640.
177. Gabriel K.I., Yu W., Ellis L., Weinberg J. Postnatal handling does not attenuate hypothalamic- pituitary-adrenal hyperresponsiveness after prenatal ethanol exposure // Alcohol. Clin. Exp. Res. - 2000. - 24, N 10. - P. 1566-1574.
178. Gabriel K.I., Weinberg J. Effects of prenatal ethanol exposure and postnatal handling on conditioned taste-aversion // Neurotoxicol. Teratol. - 2001. - 23, N 2. - P. 167-176.
179. Gandarias J.M., Irazusta J., Fernandez D., Silio M., Casis L. Membrane-bound pyroglutamyl-arylamidase activity during the first postnatal month in several rat brain areas // Int. J. Dev. Biol. - 1994. - 38, № 1. - P. 127-129.
180. Gandarias J.M., Ramirez M., Zulaica J., Casis L. Aminopeptidase (arylamidase) activity in discrete areas of the rat brain: Sex differences // Horm. Metab. Res. - 1989. - 5, № 21. - P. 285-286.
181. Genazzani A.R., Faechinetti F., Petraglia F., Pintor C., Bagnoli F., Puggioni R., Corda R. Correlations betneen plasma levels of opioid peptides and adrenal androgens in prepuberty and puberty // J. Steroid. Biochem. - 1983. - 19, № 1. - P. 891-895.
182. Glavas M.M., Hofmann C.E., Yu W.K., Weinberg J. Effects of prenatal ethanol exposure on hypothalamic-pituitary-adrenal regulation after adrenalectomy and corticosterone replacement // Alcohol. Clin. Exp. Res. - 2001. - 25, N 6. - P. 890-897.
183. Glombik M. M., Kromer A., Salm T., Huttner W. B., Gerdes H. H. The disulfide-bonded loop of chromogranin-B mediates membrane-binding and directs sorting from the trans-Golgi network to secretory granules. // EMBO J. - 1999. - 18. 4. P. 1059-1070.
184. Goldstein D. B., Chim Y. H. Interaktion of ethanol with biological membranes. // Fed. Proc. - 1981. - 40, N 7. - P. 2073-2076.
185. Gorenstein C., Snyder S., Tmo distinct enkephalinases solupilizabion, partial purification and separation from angiotensin converting enzyme // Life. Sci. - 1979. - 25. - P. 2065.
186. Graham K., Wilsnack R., Dawson D., Vogeltanz N. Should alcohol consumption measures be adjusted for gender differences // Addiction - 1998. - 93, N 8. - P. 1137-1147.
187. Grigoriants O., Devi L., Fricker L.D. Dopamine antagonist haloperidol increases carboxypeptidase E mRNA in rat neurointer-mediate pituitary but not in various other rat tissues // Mol. Brain Res. - 1993. - 19. - P. 161-164.
188. Grimwood B.G., Plummer T.H. Jr., Tarentino A.L. Carboxypeptidase H. A regulatory peptide-processing enzyme produced by human hepatoma Hep G2 cells // J. Tiolog. Chem. - 1989. - 264, N 26. - P. 15662-15667.
189. Guaza C., Borrell S. Modifications in adrenal hormones response to ethanol by prior ethanol dependence // Pharmacol. Biochem. Behav. - 1985. - 22, N 3. - P. 357-360.
190. Guerri C. Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure // Alcohol. Clin. Exp. Res. - 1998. - 22, N 2. - P. 304-312.
191. Guerri C., Renaupiqueras J. Alcohol, astroglia, and brain development // Mol. Neurobiol. - 1997. - 15, N 1. - P. 65-81.
192. Guest P.C., Arden S.D., Rutherford N.G., Hutton J.C. The posttranslational processing and intracellular sorting of carboxypeptidase H in the islets of Langerhans // Mol. Cell. Endocrinol. - 1995. - 113, N 1, P. 99-108.
193. Guest P.C., Ravazzola M., Davidson H.W., Orci L., Hutton J.C. Molecular heterogeneity and cellular localization of carboxypeptidase H in the islets of Langerhans // Endocrinology. - 1991. - 129, N 2. - P. 734-740.
194. Hall C.S. Emotional behavior in the rat. The relationship between emotionality and ambulatory activity // J. Copm. Physiol. Psychol. - 1936. - 22. - P. 345-352.
195. Hanna W.L., Turbov J.M., Jackman H.L., Tan Fulong, Froelich C.J. Dominant chymotrypsin-like esterase activity in human lymphocyte granules is mediated by the serine carboxypeptidase called cathepsin A-like protective protein // Immunol. - 1994. - 153, N 10, - P. 4663-4672.
196. Hansen L. F., Rehfeld J. F. Impaired feedback of gastric functions in carboxypeptidase E deficient mice // Biochem. and Biophysic. Res. Comm. - 2000. - 267, N 2. P. 638-642.
197. Harada S., Tachiyashiki K., Imaizumi K. Effect of sex-hormones on rat-liver cytosolic alcohol dehydrogenase activity // J Nutr. Sci. Vitaminol. - 1998, - 44, N 5, P. 625-639.
198. Hitсhison W. D., Gianoulakis С., Kalant H. Effeсt of ethanol withdrawal on Я - endorphin levels in rat brain and pituitary. // Pharm. Bioсhem. Behav. - 1988. - 30, N 4. - P. 933-939.
199. Hook V.Y. Arginine and lysine product inhibition of bovine adrenomedullary carboxypeptidase H, a prohormone processing enzyme // Life Sci. - 1990. - 47, N 13. - P. 1135-1139.
200. Hook V.Y. Carboxypeptidase B-like activity for the processing of enkephalin precursors in the membrane component of bovine adrenomedullary chromaffin granules // Neuropeptides. - 1984. - 4, N 2. - P. 117-126.
201. Hook V.Y., Affolter H.U., Palkovits M. Carboxypeptidase H in the hypothalamo neurohypophysial system: evidence for processing and activation of a prohormone processing enzyme during axonal transport // J. Neurosci. - 1990. - 10, N 10. - P. 3219-3226.
202. Hook V.Y., LaGamma E.F. Product inhibition of carboxypeptidase H // J. Biol. Chem. - 1987. - 262, N 26. - P. 12583-12588.
203. Hook V.Y., Lee E.E. Two peptidases that convert 125J-Lys-Arg-(Met)-enkephalin and 125J-enkephalin-Arg6, respectively, to 125J-(Met)-enkephalin in bovine adrenal medullary chromaffin granules // FEBS Lett. - 1984. - 172, N 2. - P. 212-218.
204. Hook V.Y., Loh Y.P. Carboxypeptidase B-like convertasing enzyme activity in secretory granules of rat pituitary // Cell Biol. - 1984. - 81. - P. 2776-2780.
205. Hook V.Y., Mezey E., Fricker L.D., Pruss R.M., Siegel R.E., Brownstein M.J. Immunochemical characterization of carboxypeptidase B-like peptide-hormone-processing enzymes // Proc. Natl. Acad. Sci. USA. - 1982. - 82. - P. 4745-4749.
206. Hook V.Y.H., Affolter H.U. Identification of zymogen and mature forms of human carboxypeptidase H. A processing enzyme for the synthesis of peptide hormones // FEBS Lett. - 1988. - 238, N 2. - P. 338-342.
207. Hook V.Y.H., Eiden L. E. Two peptidases that convert 125J-Lys-Arg-(Met)-enkephalin and 125J-enkephalin-Arg6, respectively, to 125J-(Met)-enkephalin in bovine adrenal medullary chromaffin granules // FEBS Let. - 1984. - 172, N 2. - P. 212-218.
208. Hughes P.D., Kim Y.N., Randall P.K., Leslie S.W. Effect of prenatal ethanol exposure on the developmental profile of the NMDA receptor subunits in rat forebrain and hippocampus // Alcohol. Clin. Exp. Res. - 1998. - 22, N 6. - P. 1255-1261.
209. Inder W.J., Joyce P.R., Ellis M.J., Evans M.J., Livesey J.H., Donald R.A The effects of alcoholism on the hypothalamic-pituitary-adrenal axis: interaction with endogenous opioid peptides // Clin. Endocrinol. - 1995. - 43, N 3. - P. 283-290.
210. Irminger J.C., Verchere C.B., Meyer K., Halban P.A. Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E deficient Cpe(Fat)/Cpe(Fat) mice // J. Biol. Chem. - 1997. - 272, N 44, P. 27532-27534.
211. Isenberg K.T., Bora P.S., Zhou Xia, Wu Xiaolin, Moore B. W., Lange L. G. Nonoxidative ethanol metabolism: expression of fatty aсid ethyl ester synthase-III in сultured neural сells. // Bioсhem. Biophys. Res. Сommun. - 1992. - 185, N 3. - P. 938-943.
212. Iversen I., Turner A. Neuropeptides and their peptidases: functional consideration // Neurochem. Intern. - 1987. - 12. - P. 383-387.
213. Jin K. L., Graham S. H., Nagayama T., Goldsmith P. C., Greenberg D. A., Zhou A., Simon R. P. Altered expression of the neuropeptide processing enzyme carboxypeptidase-E in the rat brain after global ischemia. // J. Cerebr. Blood Flow Metabol. - 2001. - 21. N 12. P. 1422-1429.
214. Juarez J., Detomasi E.,B. Sex differences in alcohol drinking patterns during forced and voluntary consumption in rats // Alcohol - 1999. - 19, N 1. - P. 15-22.
215. Jung M.E., Wallis C.J., Gatch M.B., Lal H. Sex differences in the pentylenetetrazol-like stimulus- induced by ethanol withdrawal // J Pharmacol. Exp. Ther. - 1999. - 291, N 2. - P. 576-582.
216. Jung M.E., Wallis C.J., Gatch M.B., Lal H. Sex-differences in nicotine substitution to a pentylenetetrazol discriminative stimulus during ethanol withdrawal in rats // Psychopharmacology - 2000. - 149, N 3. - P. 235-240.
217. Jung M.E., Wallis C.J., Gatch M.B., Lal H. Sex-differences in the discriminative stimulus effects of M-chlorophenylpiperazine and ethanol withdrawal // Psychopharmacology - 2000. - 149, N 2. - P. 170-175.
218. Jung Y.K., Fricker L. D. Expression of the carboxypeptidase-E gene - characterization of the initiator-binding proteins // Biochimie. - 1994. - 76. N 3-4. - P. 336-345.
219. Jung Y.K., Kunczt C.J., Pearson R.K., Dixon J.E., Fricker L.D. Structural characterization of the rat carboxypeptidase-E gene. // Mol. Endocrinol. - 1991. - 5, N 9. - P. 1257-1268.
220. Jung Y.K., Kunczt C.J., Pearson R.K., Fricker L.D., Dixon J.E. Expression of the rat carboxypeptidase-E gene in neuroendocrine and nonneuroendocrine cell lines // Mol. Endocrinol. - 1992. - 6, N 12. - P. 2027-2037.
221. Juvvadi S., Fan X.M., Nagle G.T., Fricker L.D. Characterization of aplysia carboxypeptidase E // FEBS Lett. - 1997. - 408, N 2, P. 195-200.
222. Keith L.D., Crabbe J.C., Robertson L.M., Young E.R. Ethanol dependence and the pituitary adrenal axis in mice. II. Temporal analysis of dependence and withdrawal // Life Sci. - 1983. - 33, N 19. - P. 1889-1897.
223. Kenney W. C. Formation of Schiff base adduct between acetaldehyde and rat liver microsomal phosphatidylethanolamine. // Alcohol. Clin. Exp. Res. - 1984. - 8, N 6. - P. 551-555.
224. Kim C.K., Yu W., Edin G., Ellis L., Osborn J.A., Weinberg J. Chronic intermittent stress does not differentially alter brain corticosteroid receptor densities in rats prenatally exposed to ethanol // Psychoneuroendocrinology - 1999. - 24, N 6. - P. 585-611.
225. Kimura K.A., Chiu J., Reynolds J.N., Brien J.F. Effect of chronic prenatal ethanol exposure on nitric oxide synthase-I and synthase-III proteins in the hippocampus of the near term fetal guinea pig // Neurotoxicol. Teratol. - 1999. - 21, N 3. - P. 251-259.
226. Kimura K.A., Reynolds J.N., Brien J.F. Ethanol neurobehavioral teratogenesis and the role of the hippocampal glutamate-N-methyl-D-aspartate receptor - nitric oxide synthase system // Neurotoxicol. Teratol. - 2000. - 22, N 5. - P. 607-616.
227. King J.C., Fabro S. Alcohol counsumption and cigarette smoking: effect on pregnancy // Clin. Obstet. Gynecol. - 1983. - 26. - P. 437-448.
228. Kinoshita, Jessop/
229. Klein R. S., Das B., Fricker L. D. Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cell, a neuroendocrine cell line: implications for neuropeptide biosynthesis // J. Neurochim. - 1992. - 58. N 6. - P. 2011-2018.
230. Kluger M.J. Fever: vole of pyrogens and cryagens // Physiol. Rev. - 1991. - 71. - P. 93.
231. Krahl S.E., Berman R.F., Hannigan J.H. Electrophysiology of hippocampal Ca1 neurons after prenatal ethanol exposure // Alcohol - 1999. - 17, N 2. - P. 125-131.
232. Kuhn P.E., Miller M.W. Expression of p53 and Alz-50 immunoreactivity in rat cortex - effect of prenatal exposure to ethanol // Exp. Neurol. - 1998. - 154, N 2. - P. 418-429.
233. Kulkosky P.J., Allison C.T., Allison T.G., Marquez L.M., Mattson B.J. Interaction of CCK and 8-Oh-Dpat in the satiation of alcohol intake // Alcohol - 1998. - 16, N 4. - P. 305-309.
234. Kulkosky P. J., Allison C. T., Mattson B. J. Thyrotropin releasing hormone decreases alcohol intake and preference in rats. //Alcohol. - 2000. - 20, N 1. - P. 87-91.
235. Kulkosky P. J., Clayborne Y. J., Sandoval S. L. Cholecystokinin and bombesin inhibit ethanol and food intake in rats selectively bred for ethanol sensitivity. // Alcohol. Clin. Exp. Res. - 1993. - 17, N 3. - P. 545-551.
236. Lacourse K.A., Friishansen L., Rehfeld J.F., Samuelson L.C. Disturbed progastrin processing in carboxypeptidase E deficient fat mice // FEBS Lett. - 1997. - 416, N 1. - P. 45-50.
237. Laslop A., Tschernitz C. Effects of nerve growth factor on the biosynthesis of chromogranin A and B, secretogranin II and carboxy-peptidase H in rat PC12 cells // Neuroscience. -1992. - 49, N 2. - P. 443-450.
238. Li T.K. Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking. // J. Stud. Alcohol. - 2000. - 61, N 1. - P. 5-12.
239. Li Y., McGivern R.F., Nagahara A.H., Handa R.J Alterations in the estrogen sensitivity of hypothalamic proenkephalin mRNA expression with age and prenatal exposure to alcohol // Molecular Brain Research - 1997. - 47, N 1-2. - P. 215-222.
240. Lingfordhughes A.R., Acton P.D., Gacinovic S., Boddington S.J.A., Costa D.C., Pilowsky L.S., Ell P.J., Marshall E.J., Kerwin R.W. Levels of gamma-aminobutyric acid-benzodiazepine receptors in abstinent, alcohol-dependent women - preliminary findings from an I-123 lomazenil single- photon-emission-tomography study // Alcohol. Clin. Exp. Res. - 2000. - 24, N 9. - P. 1449-145.
241. Livy D.J., Maier S.E., West J.R. Fetal alcohol exposure and temporal vulnerability - effects of binge like alcohol exposure on the ventrolateral nucleus of the thalamus // Alcohol. Clin. Exp. Res. - 2001. - 25, N 5. - P. 774-780.
242. Loh Y.P., Brownstein M.J., Gainer H. Proteolysis in neuropeptide processing and ofker neurol functions // Ann.Rev.Neurosci. - 1984. - 7. - P. 183-185.
243. Loh Y.P., Snell C.R., Cool D.R. Receptor mediated targeting of hormones to secretory granules, role of carboxypeptidase E // Trends Endocrinol. Met. - 1997. - 8, N 4, P. 130-137.
244. Lowry O.H., Rosebrought N.J., Farr A.G., Randall R.J. Protein measurement with Folin phenol reagent // J. Biol. Chem. - 1951. - 193, N 1. - P. 265-275.
245. Luсas D., Penneс Y., Menez J. F., Floch H. H., Menn G. Le. Acetaldehyde adducts with serum proteins are not responsible for decreased drug binding in alcoholic patients. // Drug Alс. Depend. - 1986. - 17, N 1. - P. 67-71.
246. Lynch D.R., Braas K.M., Hutton J.C., Snyder S.H. Carboxypeptidase E (CPE) immunocytochemical localization in the rat central nervous system and pituitary gland // J. Neurosci. - 1990. - 10. - N 5. - P. 1592-1599.
247. Lynch D.R., Snyder S.M. Neuropeptides: multiple forms, metabolic pathnays and receptors // Ann. Rev. Biochem. - 1986. - 55. - P. 773-799.
248. Lynch D.R., Venable J.C., Snyder S.H. Enkephalin convertase in the heart: similar disposition to atrial natriuretic factor // Endocrinology. - 1988. - 122, N 6. - P. 2683-2691.
249. Lynch D.R., Venable J.C., Strittmatter S.M., Snyder S.H. Enkephalin convertase: charasterization and localization using [3H]guanidinoethyl-mercaptosuccinic acid // Biochimie. - 1988. - 70, N 1. - P. 57-64.
250. MacCumber M.W., Snyder S.H., Ross C.A. Carboxypeptidase E (enkephalin convertase): mRNA distribution in rat brain by in situ hybridization // J. Neurosci. - 1990. - 10, N 8. - P. 2850-2860.
251. Mackin R.B., Noe B.D. Charasterization of an islet carboxypep-tidase B involved in prohormone processing // Endocrinology. - 1987. - 120, N 2. - P. 457-468.
252. Maier S.E., West J.R. Regional differences in cell loss associated with binge- like alcohol exposure during the first 2 trimesters equivalent in the rat // Alcohol - 2001. - 23, N 1. - P. 49-57.
253. Mains R.E., Eipper B.A. Secretion and regulation of two biosyntetic enzyme activities, peptidyl-glycine -amidating monooxygenase and a carboxypeptidase, by mouse pituitary corticotropic tumor cells // Endocrinology. - 1984. - 115, N 5. - P. 1683-1690.
254. Maletti M., Besson J., Bataille D., Laburthe M., Rosselin M. Ontogenesis and immunoreactive forms of vasoactive intestinal peptide in rat brain // Acfa Endocrinol. - 1980. - 93, № 4. - P. 479-487.
255. Manser E., Fernandez D., Loo L., Goh P.Y., Monfries C., Hall C., Lim L. Human carboxypeptidase E., Isolation and characterization of the cDNA, sequ-ence conservation, expression and processing in vitro // Biochem. J. 1990. - 267, N 2. - P. 517-525.
256. Marks N., Berg N., Benuck M., Lo E.S., Novachenko H., Seyfried C. Prodynorphin processing by rat CNS fractions and purified enzyme: formation of dynorphin A 1-8 by sulfhydryl activated carboxypeptidase and peptidyl dipeptidase // Neurochem. Intern. - 1987. - 10, N 4. - P. 413-422.
257. Marks N., Grynbaum A., Benuck M. On the sequential cleavage of myelin basic protein by cathepsin A and D // J. Neurochem. - 1976. N 27. - P. 765-768.
258. Marks N., Stern F., Lajtha A. Changes in proteolytic enzymes and proteins during maturation of the brain // Brain Res. - 1975. - 86, № 2. - P. 307-322.
259. Martinez-Millan L., De Gandaries J.M., Irazusta J., Echevarria E., Casis L. Developmental changes of amino peptidase activity in the cortex of the cat hrain // Int. J. Dev. Neurosci. - 1993. - 11, № 1. - P. 11-15.
260. Mathieu-Kia A. M., Resson M. J. Repeatet administration of сoсaine, niсotine and ethanol: effeсts on preprodynorphin, preprotaсhykinin H and preproenkephalin mRNA expression in the dorsal and the ventral striatum of the rat // Moleс. Brain Res. - 1998. - 54. - P. 141-151.
261. Matsas R., Kenny A.S., Turner A.J. An immunohistochemical study of endopeptidase 24.11 (enkephalinase) in the pig nervous system // Neuroscience. - 1986. - 18, № 4. - P. 991-996.
262. McDonald J.K., Schwabe C. Intracellular exopeptidase // Proteinases in mammalian cells and tissues / Barrett A.J. (ed.). Amsterdam: Elsevier/North Holland Biomedical Press - 1977. - P. 311-391.
263. McGivern R.F., Clancy A.N., Mousa S., Couri D., Noble E.P. Prenatal alcohol exposure alters enkephalin levels, without affecting ethanol preference // Life Sci. - 1984. - 34, N 6. - P. 585-589.
264. McGivern R.F., Ervin M.G., Mcgeary J., Somes C., Handa R.J. Prenatal ethanol exposure induces a sexually dimorphic effect on daily water-consumption in prepubertal and adult rats // Alcohol. Clin. Exp. Res. - 1998. - 22, N 4. - P. 868-875.
265. McGivern R.F., Handa R.J., Raum W.J. Ethanol exposure during the last week of gestation in the rat - inhibition of the prenatal testosterone surge in males without long-term alterations in sex behavior // Neurotoxicol. Teratol. - 1998. - 20, N 4. - P. 483-490.
266. McMillian M.K., Hudson P.M., Lec D.Y., Thai L., Hung G.H., Hong J.S. Developmental changes . in rat adrenal enkephalin premrsor: peptide ratio // Brain. Res. Dev. Brain. Res. - 1993. - 71, № 1. - P. 75-80.
267. Meunier J.-C. The opioid peptides and their receptors // Biochimie. - 1986. - 68. - P. 1153-1158.
268. Mihalick S.M., Crandall J.E., Langlois J.C., Krienke J.D., Dube W.V. Prenatal ethanol exposure, generalized learning impairment, and medial prefrontal cortical deficits in rats // Neurotoxicol. Teratol. - 2001. - 23, N 5. - P. 453-462.
269. Miller M.W. A longitudinal study of the effects of prenatal ethanol exposure on neuronal acquisition and death in the principal sensory nucleus of the trigeminal nerve - interaction with changes induced by transection of the infraorbital nerve // J Neurocytol - 1999. - 28, N 12. - P. 999-1015.
270. Mitra A., Song L.X., Fricker L.D. The C-terminal region of carboxypeptidase E is involved in membrane-binding and intracellular routing in AtT-20 cells // J. Biol. Chem. - 1994. - 269, N 31. - P. 19876-19881.
271. Moore D.B., Ruygrok A.C., Walker D.W., Heaton M.B. Effects of prenatal ethanol exposure on parvalbumin expressing GABAergic neurons in the adult rat medial septum // Alcohol. Clin. Exp. Res. - 1997. - 21, N 5. - P. 849-856.
272. Mourik J., Raeven P., Steur K., Addink A.D.F. Anatrobic metabolism of red skeletsl muscle of goldfish, Carassius auratus (L). Mitochondrial produced acetaldehyde as anaerobic electron acceptor // FEBS Lett. - 1982. - 137, N 1. Р. 111-114.
273. Naggert J.K., Fricker L.D., Varlamov O., Nishina P.M., Rouille Y., Steiner D.F., Carroll R.J., Paigen B.J., Leiter E.H. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity // Nature Genetics. - 1995. - 10, N 2. - P. 135-142.
274. Nalamachu S.R., Song L.X., Fricker L.D. Regulation of carboxypeptidase E - effect of Ca2+ on enzyme-activity and stability // J. Biol. Chem. - 1994. - 269, N 15. - P. 11192-11195.
275. Nemeskeri A., Acs Z., Toth B.E. Prolactin-synthesiring and prolactin-releasing activity of fetal andeurly postnatal rat piluitaries: in vivo and in vitro studies using RIA, reverse hemolytic plaque assay and immunocytochemistry. // Neuroendocrinology. - 1995. - 61. - P. 687-694.
276. Nolan C.J., Bestervelt L.L., Mousigian C.A., Maimansomsuk P., Cai Y., Piper W.N. Chronic ethanol consumption depresses hypothalamic-pituitary-adrenal function in aged rats // Life Sci. - 1991. - 49, N 25. P. 1923-1928.
277. Norenberg U., Richter D. Processing of the oxytocin precursor: isolation of an exopeptidase from neurosecretory granules of bovine pituitaries // Biochem. Biophys. Res. Commun. - 1988. - 156, N 2. - P. 898-904.
278. Oakes M. G., Davis T. P. The ontogeny of enzymes involved in post-translational processing and metabolism of neuropeptides. // Dev. Brain Res. - 1994. - 80. N 1-2. P. 127-136.
279. Orskov C., Buhl T., Rabenhoj L., Kofod H., Holst J. J. Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine // FEBS Lett. - 1989. - 247, N 2. P. 193-196.
280. Osborn J.A., Kim C.K., Steiger J., Weinberg J. Prenatal ethanol exposure differentially alters behavior in males and females on the elevated plus-maze // Alcohol. Clin. Exp. Res. - 1998. - 22, N 3. - P. 685-696.
281. Osborn J.A., Yu C., Gabriel K., Weinberg J. Fetal ethanol effects on benzodiazepine sensitivity measured by behavior on the elevated plus-maze // Pharmacol. Biochem. Behav. - 1998. - 60, N 3. - P. 625-633.
282. Osborn J.A., Yu C., Stelzl G.E., Weinberg J. Effects of fetal ethanol exposure on pituitary-adrenalsSensitivity to secretagogues // Alcohol. Clin. Exp. Res. - 2000. - 24, N 7. - P. 1110-1119.
283. Oyarce A.M., Hand T.A., Mains R.E., Eipper B.A. Dopaminergic regulation of secretory granule associated proteins in rat intermediate pituitary // J. Neurochem. - 1996. - 67, N 1. - P. 229-241.
284. Ozer E., Sarioglu S., Gure A. Effects of prenatal ethanol exposure on neuronal migration, neuronogenesis and brain myelination in the mice brain // Clin. Neuropatol. - 2000. - 19, N 1. - P. 21-25.
285. Parkinson D. Carboxypeptidase H in bovine pituitary gland: soluble forms are not processed at the C-terminus // Mol. Cell. Endocrinol. - 1992. - 86, N 3. - P. 221-233.
286. Parkinson D. Two soluble forms of bovine carboxypeptidase H have different NH2-terminal sequences // J. Biol. Chem. - 1990. - 265, N 28. - P. 17101-17105.
287. Perloff M.D., Kream RM., Beinfeld M.C. Reduced levels of substance P in the brains of Cpe(Fat)/Cpe(Fat) Mice // Peptides. - 1998. - 19, N 6, P. 1115-1117.
288. Prendergast M.A., Harris B.R., Blanchard J.A., Mayer S., Gibson D.A., Littleton J.M. In-vitro effects of ethanol withdrawal and spermidine on viability of hippocampus from male and female rat // Alcohol. Clin. Exp. Res. - 2000. - 24, N 12. - P. 1855-1861.
289. Pshezhetsky A.V., Potier M. Direct affinity purification and supramolecular organization of human lysosomal cathepsin A // Arch. Biochem. Biophys. - 1994. - 313, N 1. - P. 64-70.
290. Rasmussen D.D., Boldt B.M., Bryant C.A., Mitton D.R., Larsen S.A., Wilkinson C.W. Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypothalamo-pituitary-adrenal axis // Alcohol. Clin. Exp. Res. - 2000. - 24, N 12. - P. 1836-1849.
291. Revskoy S., Halasz I., Redei E. Corticotropin-releasing hormone and proopiomelanocortin gene expression Is altered selectively in the male rat fetal thymus by maternal alcohol consumption // Endocrinology - 1997. - 138, N 1. - P. 389-396.
292. Reznik S. E., Salafia C. M., Lage J. M., Fricker L. D. Immunohistochemical localization of carboxypeptidase-E and carboxypeptidase-D in the human placenta and umbilical-cord // J. Histochem.and Cytochem. - 1998. - 46, N 12. P. 1359-1367.
293. Rikke B.A., Simpson V.J., Montoliu L., Johnson T.E. No effect of albinism on sedative-hypnotic sensitivity to ethanol and anesthetics // Alcohol. Clin. Exp. Res. - 2001. - 25, N 2. - P. 171-176.
294. Rintala J., Jaatinen P., Lu W., Sarviharju M., Eriksson C.J.P., Laippala P., Kiianmaa K., Hervonen A. Effects of lifelong ethanol consumption on erebellar layer volumes in AA and ANA rats // Alcohol. Clin. Exp. Res. - 1997. - 21, N 2. - P. 311-317.
295. Rivier C. Female rats release more corticosterone than males in response to alcohol: influence of circulating sex steroids and possible consequences for blood alcohol levels. // Alcohol. Clin. Exp. Res. - 1993. - 17. N. 4. - P. 854-859.
296. Rivier C., Bruhn T., Vale W. Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF) // J. Pharmacol. Exp. Ther. - 1984. - 229, N 1. - P. 127-131.
297. Rivier C., Imaki T., Vale W. Prolonged exposure to alсohol: effeсt on сRF mRNA levels, and CRF - and stress-induсed ACTH seсretion in the rat // Brain Res. - 1990. - 520, N 1-2. - P. 1-5.
298. Rivier C., Rivest S., Vale W. Alcohol-induced inhibition of LH secretion in intact and gonadectomized male and female rats: possible mechanisms // Alcohol. Clin. Exp. Res. - 1992. - 16, N 5. - P. 935-941.
299. Rockman C.E., Markert L.E., Delrizzo M. Effects of prenatal ethanol exposure on ethanol-induced locomotor activity in rat // Alcohol. - 1989. - 6, N 5. - P. 353-356.
300. Rodriguez C., Brayton K.A., Brownstein M., Dixon J.E. Rat preprocarboxypeptidase H. Cloning, characterization, and sequence of the cDNA and regulation of the mRNA by corticotropin releasing factor // J. Biol. Chem. - 1989. - 264, N 10. - P. 5988-5995.
301. Rossier, J., Barres, E., Hutton, J.C., Ricknell, R.J. Radiometric assay for carboxypeptidase H (EC 3.4.17.10) and other carboxypeptidase B-like enzymes // Anal. Biochem. - 1989. - 178, N 1. - P. 27-31.
302. Rouille Y., Chauvet J., Acher R. Partial conversion of vasopressinyl-Gly-Lys-Arg into pharmacologically active vasopressin through secretory granule carboxypeptidase E and alpha-amidating processing enzymes // Biochem. Int. - 1992. - 26, N 4. - P.739-746.
303. Rovere C., Viale A., Nahon J., Kitabgi P. Impaired processing of brain proneurotensin and promelanin concentrating hormone in obese fat/fat mice // Endocrinology. - 1996. - 137, N 7. - P. 2954-2958.
304. Roy A., Mittal N., Zhang H., Pandey S. C. Modulation of cellular expression of glucocorticoid receptor and glucocorticoid response element-DNA dinding in rat brain during alcohol drinking and withdrawal // J. Pharmacol. Exp. Ther. - 2002. - 301, N 2, - P. 774-784. ХЭ364
305. Salonen I., Huhtaniemi I. Effects of chronic ethanol diet on pituitary-testicular function of the rat // Biol. Reprod. -1990. - 42. P. 55-62.
306. Sarviharju M., Jaatinen P., Hyytia P., Hervonen A., Kiianmaa K. Effects of lifelong ethanol consumption on drinking behavior and motor impairment of alcohol-preferring AA and alcohol-avoiding ANA rats // Alcohol - 2001. - 23, N 3. - P. 157-166.
307. Scarceriaux V., Pelaprat D., Lhiaubet A.M., Schimptf R.M., Tramu G., Rostene W. Developmental pattern of neurofensin content in rat hypothalamic neurons culbured in serum free medium-comparison with in vivo data // Dev. Brain Res. - 1994. - 81, № 1. - P. 128-130.
308. Schlamp C.L., Nickells R.W. Light and dark cause a shift in the spatial expression of a neuropeptide processing enzyme in the rat retina // J. Neurosci. - 1996. - 16, N 7. - P. 2164-2171.
309. Schneider M.L., Moore C.F., Kraemer G.W. Moderate alcohol during pregnancy - learning and behavior in adolescent Rhesus-Monkeys // Alcohol. Clin. Exp. Res. - 2001. - 25, N 9. - P. 1383-1392.
310. Seizinger B.R., Brinn C., Herr A. Evidence for a differential postnatal development of proenkephalin B (prodynorphin) - derived opieid peptides in the rat hypothalamus // Endocrinology. - 1984. - 115, № 3. - P. 926-935.
311. Shen F.S., Loh Y.P. Intracellular Misrouting and Abnormal Secretion of Adrenocorticotropin and Growth Hormone in Cpe (Fat) Mice Associated with a Carboxypeptidase E Mutation // Proc. Nat. Acad. Sci. USA. - 1997. - 94, N 10. - P. 5314-5319.
312. Silva W.I., Benitez K., Ocasio J., Martinez L., Rosario N. Neuropeptide like immunoreactivities and carboxypeptide H activity associated with bovine brain clathrin coated vesicles // Neuropeptides. -1995. - 28, N 6, P. 341-349.
313. Sinha P., Halasz I., Choi J.F., Mcgivern R.F., Redei E. Maternal adrenalectomy eliminates a surge of plasma dehydroepiandrosterone in the mother and attenuates the prenatal testosterone surge in the male fetus // Endocrinology - 1997. - 138, N 11. - P. 4792-4797.
314. Skutohness C.D., Holroyde C.P., Nyers R.N. et al. Acetat in normal human blood // J. Clin. Invest. - 1979. - 64. - P. 708-713.
315. Sluyter F., Hof M., Ellenbroek B.A., Degen S.B., Cools A.R. Genetic, sex, and early environmental-effects on the voluntary alcohol - intake in Wistar rats // Pharmacol. Biochem. Behav. - 2000. - 67, N 4. - P. 801-808.
316. Smith D.R., Pallen C.J., Murphy D., Lim L. Pituitary-specific transcriptional initiation sites of the rat carboxypeptidase-H gene and the influence of thyroid hormone status // Mol. Endocrinol. - 1992. - 6, N 5. - P. 713-722.
317. Smyth D.G., Maruthainar K., Darby N.J., Fricker L.D. Catalysis of slow C terminal processing reactions by carboxypeptidase H // J. Neurochem. - 1989. - 53, N 2. - P. 489-493.
318. Song L.X, Fricker L.D. Calcium and pH dependent aggregation of carboxypeptidase E // J. Biol. Chem. - 1995. - 270, N 14. - P. 7963-7967.
319. Song L.X., Fricker L.D. The pro region is not required for the expression or intracellular routeing of carboxypeptidase E // Biochemical Journal. - 1997. - 323, N 4. - P. 265-271.
320. Spencer R.L., McEwen B.S. Impaired adaptation of the hypothalamic-pituitary-adrenal axis to chronic ethanol stress in aged rats // Neuroendocrinol. - 1997. - 65, N 5. - P. 353-359.
321. Spenсer R. L., MсEwen B. S. Adaptation of the hypothalamiс- pituitary-adrenal axis to сhroniс ethanol stress. // Neuroendoсrinology. - 1990. - 52, N 5. - P. 481-489.
322. Srivastava V.K., Hiney J.K., Dearth R.K., Les Dees W. Chronic effects of prepubertal ethanol administration on steroidogenic acute regulatory protein in the rat ovary.// Alcohol. Clin. Exp. Res. - 2002. - 26, N 1. - P. 107-113.
323. Stack G., Fricker L.D., Snyder S.H. A sensitive radiometric assay for enkephalin convertase and for carboxypeptidase B-like enzymes // Life Sci. - 1984. - 34. - P. 113-121.
324. Stege T. E. Induсtion of aсetaldehyde lipid peroxidation in hepatiс сell. // Reс. Commun. Chem. Phatal. Pharmaсol. - 1982. - 36, N 2. - P. 287-297.
325. Stone T.E., Li J.P., Bernasconi P. Purification and Characterization of the Manduca Sexta Neuropeptide Processing Enzyme Carboxypeptidase E // Arch. Insect Biochem. Phisiol. - 1994. - 27, N 3, P. 193-203.
326. Strittmatter S.M., Lynch D.R., Skyder S.H. Differential ontogeny of rat brain peptidases: prenatal expression of enkephalin convertase and postnatal development of angiotensin converting enzyme // Dev. Brain. Res. - 1986. - 29, № 2. - P. 207-215.
327. Strittmatter S.M., Lynch D.R., Snyder S.H. (3H)guanidinoethyl-mercaptosuccinic acid binding to tissue homogenates. Selective labeling of enkephalin convertase // J. Biol. Chem. - 1984. - 259, N 19. - P. 11812-11817.
328. Sullivan K.A., Traurig H.H., Papka R.E. Ontogeny of neurotransmitter system in the paracervical ganglion and uterine cervix of the rat // Anat. Rec. - 1994. - 240, № 3. - P. 377-386.
329. Summers M. L., Gidley M. S., Sanders S. K. Aсetaldehydeenkephalins: eluсidation of the struсture of the aсetaldehyde adduсts of methionine-enkephalin and leuсine- enkephalin. // FEBS. - 1980. - 111, N 2. - P. 307-310.
330. Supattapone S., Fricker L.D., Snyder S.H. Purification and characterization of a membrane-bound enkephalin-forming carboxypeptidase, “enkephalin convertase” // Neurochem. - 1984. - 42, N 4. - P. 1017-1023.
331. Szot P., White S.S., Veith R.C., Rasmussen D.D. Reduced gene expression for dopamine biosynthesis and transport in midbrain neurons of adult male rats exposed prenatally to ethanol // Alcohol. Clin. Exp. Res. - 1999. - 23, N 10. - P. 1643-1649.
332. Tabakoff B., Hoffman P. L., Litjequist S. Effeсts of ethanol on the aсtivity of brain enzymes. // Enzyme. - 1987. - 37, N 1-2. - P. 70-86.
333. Taylor A.N., Branch B.J., Day J.R., Lu J.K.H. Alcohol effects progesterone, testosterone and prolactin secretionin pragnant rats // 31th Congr. Physiol. Sci. - Helsinki, 1989. - P. 538-540.
334. Tesсhke R., Hasumura V., Lieber Сh. S. Hepatiс ethanol metabolism: respeсtive roles of alсohol dehydrogenate, the miсrosomal ethanol-oxidizing system and сatalase. // Arсh. Bioсhem. - 1976. - 175. - P. 635-643.
335. Tschernitz C, Laslop A, Eiter C, Kroesen S, Winkler H. Biosynthesis of large dense core vesicles in PC12 cells: effects of depolarization and second messengers on the mRNA levels of their constituets // Brain. Res. Mol. Brain Res. - 1995. - 31, N 1-2. - P. 131-140.
336. Udupi V., Gomez P., Song L.X., Varlamov O., Reed J.T., Leiter E.H., Fricker L.D., Greeley G.H. Effect of carboxypeptidase E deficiency on progastrin processing and gastrin messenger ribonucleic acid expression in mice with the fat mutation // Endocrinology. - 1997. - 138, N 5, P. 1959-1963.
337. Van Thiel D. H., Tarter R. E., Rosenblum E., Gavaler J. S. Ethanol, its metabolism and gonadal effeсts: does sex make a defferenсe? // Adv. Alсohol. Subst. Abuse. - 1988. - 7, N 3-4. - P. 131-169.
338. Varlamov O., Fricker L.D. The C terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing // J. Biol. Chem. - 1996. - 271, N 11. - P. 6077-6083.
339. Varlamov O., Fricker L.D., Furukawa H., Steiner D.F., Langley S.H., Leiter E.H. Beta cell lines derived from trans genic Cpe(Fat)/Cpe(Fat) mice are defective in carboxypeptidase E and proinsulin processing // Endocrinology. - 1997. - 138, N 11, P. 4883-4892.
340. Varlamov O., Leiter E.H., Fricker L. Induced and spontaneous mutations at Ser202 of carboxypeptidase E. Effect on enzyme expression, activity, and intracellular routing // J. Biol. Chem. - 1996. - 271, N 24. - P. 13981-13986.
341. Vernigora A.N., Gengin M.T., Shtchetinina N.V., Nikishin N.N. Comparision of long-term effect of ethanol, tranquillizers and emotional stress on activity of some neuropeptide metabolism enzyme // Neurochemistry and pharmacology of drug addiction and alcoholism: Proc. Int. Conf. (S.-Petersburg, 1996). - S.-Petersburg: Inst. of the Human Brain, 1996. - P. 70.
342. Vida M.I.R., Kleid M.C., Ase A., Finkielman S., Nahmond V.E., Vindrola O. Synenkephalin processing in embryonic rat brain // Dev. Brain. Res. - 1994. - 77, № 2. - P. 151-156.
343. Vivian J.A., Green H.L., Young J.E., Majerksy L.S., Thomas B.W., Shively C.A., Tobin J.R., Nader M.A., Grant K.A. Induction and maintenance of ethanol self-administration in cynomolgus monkeys (Macaca-Fascicularis) - long-term characterization of sex and individual-differences // Alcohol. Clin. Exp. Res. - 2001. - 25, N 8. - P. 1087-1097.
344. Wallace E.F., Evans C.J., Jurik, S.M., Mettord I.N., Barchas J.D. Carboxypeptidase B activity from adrenal medulla - is it involved in the processing of proenkephalin. // Life Sci. - 1982. - 31, N 16-17. - P. 1793-1796.
345. Wand G.S., Dobs A.S. Alterations in the hypothalamic-pituitary-adrenal axis in actively drinking alcoholics // J. Clin. Endocrinol. Metabol. -1991. - 72. - P. 1290-1295.
346. Wardlaw S.L. Regulation of -endorphin, corticotropin - like intermediate lobe hypothalamus by testosterone // Endocrinology. - 1986. - 119, № 1. - P. 19-24.
347. Weisman B.A., Azov R., Sarne Y. Ontogenesis of enkephalin and humoral andorphin in the rat brain // Neurochem. Int. - 1983. - 5, № 1. - P. 113-116.
348. Wilkinson с. M., сrabbe J. с., Keith L. D., Kendall J. W., Dorsa D. M. Influenсe of ethanol dependenсe on regional brain сontent of Я -endorphin in the mouse. // Brain Res. - 1986. - 378, N 1. - P. 107-114.
349. Woodkams P.L., Allen Y.S., McGovern J., Allen J.M., Bloom S.R., Balars R., Polrak J.M. Immunohistochemical analysis of early ontogeny of the neuropeptide Y system in rat brain // Neurosci. - 1985. - 15. - P. 173-202.
350. Yajima R., Chikuma T., Kato T. A rapid anterograde axonal transport of carboxypeptidase H in rat scia-tic nerves // J. Neurochem. - 1994. - 63, N 3, P. 997-1002.
351. Zagon I.S., Isayama T., Melaughlin P.J. Preproenkepkalin messenger RNA expression in the developing and adult rat brain // Mol. Brain Res. - 1994. - 21, № 1-2. - P. 85-98.
352. Zamir N., Weber E., Palkovits M., Brownstein M., Differential processing of prodynorphin and proenkephalin in specific regions of the rat brain // Proc. Natl. Acad. Sci. USA. - 1984. - 81. - P. 6886-6889.
353. Zheng M., Streck R.D., Scott R.E.M., Seidah N.G., Pintar J.E. The developmental expression in rat of proteases furin, Pc 1,Pc 2, and carboxypeptidase E-implications for carly maturation of proteolytic processing capacity // J.Nourosci. - 1994. - 14, № 8. - P. 4656-4673. ...........
Страницы: 1 | 2 | 3 | 4 | [5] |
|